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Acute myeloid leukemia with concomitant expression of T-/B-lymphoid antigens and immunogenotypic alterations
K Kawakubo1, K Ohyashiki, J H Ohyashiki
1First Department of Internal Medicine, Tokyo Medical College, Japan.
Leukemia
|June 1, 1993
Abstract:
We report here a patient with acute myeloid leukemia (AML) expressing both T- and B-lymphoid-associated antigens. The leukemia cells in this case had rearrangements of not only immunoglobulin heavy-chain but also T-cell-receptor beta- and delta-chain genes. Although a relatively large number of AML patients with lymphoid markers have been reported, only about a dozen AML patients expressing both T- and B-lymphoid markers have been reported so far.