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Genetics of heat-curability of killer virus of yeast
L A Weinstein1, F Capaldo-Kimball, M J Leibowitz
1Department of Molecular Genetics and Microbiology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Piscataway 08854-5635.
Yeast (Chichester, England)
|April 1, 1993
Abstract:
The cytoplasmically inherited M double-stranded (ds) RNA genome segment of killer virus of Saccharomyces cerevisiae is heat-curable in some yeast strains but not in others. Temperature sensitivity is conferred on both M1 and M2 dsRNA satellite virus segments by the L-A-HN allele of the killer helper virus genome, but not by the L-A-H allele. Both diploidy and mating type heterozygosity of the host cell are also correlated with increased virus curability.