Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Plasmid replication and maintenance in binary fissile microorganisms

A Dunn, M Day, P Randerson

    Endeavour
    |March 1, 1993
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Rapid control of an outbreak of carbapenemase-producing enterobacterales in a recently built, single-bedded, specialist cardiothoracic hospital in England.

    The Journal of hospital infection·2026
    Same author

    In sickness and health? Examining the co-occurrence and concordance of healthy lifestyle behaviours among spouses in Namibia.

    Public health·2024
    Same author

    PUF60-related developmental disorder: A case series and phenotypic analysis of 10 additional patients with monoallelic PUF60 variants.

    American journal of medical genetics. Part A·2023
    Same author

    Return to sport and beyond following intramuscular tendon hamstring injury: A case report of an English Premier League football player.

    Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine·2022
    Same author

    COVID-19: transferring learning from the pandemic response to non-communicable disease control.

    Public health·2021
    Same author

    Evaluating an 'incident control' approach to non-communicable disease.

    Public health·2021
    Same journal

    Don't Let Elon Musk Convince You that AI is the Bad Guy: A Film Review of Good Luck, Have Fun, Don't Die, Directed by Gore Verbinski. Briarcliff Entertainment, 2026.

    Endeavour·2026
    Same journal

    WITHDRAWN: Feathered architects: Collecting histories of anthropogenic material in birds' nests.

    Endeavour·2026
    Same journal

    Editorial.

    Endeavour·2026
    Same journal

    "We shall do all we can to help you": The Society for Protection of Science and Learning's interwar attempt to aid refugee orthopedists and oncologists.

    Endeavour·2026
    Same journal

    The Welwitsch Study Set: A collection ecology.

    Endeavour·2026
    Same journal

    Giant bones and giants' bodies: Collection ecologies, 1500-1700.

    Endeavour·2026
    See all related articles

    This study explores how nonconjugative plasmids replicate within a single cell and persist in bacterial populations, focusing on Escherichia coli. Understanding these mechanisms is key for genetic engineering and maximizing recombinant product yields.

    Area of Science:

    • Microbiology
    • Molecular Biology
    • Genetic Engineering

    Background:

    • Nonconjugative plasmids are crucial genetic elements for both natural microbial populations and biotechnology.
    • Understanding plasmid replication and stable inheritance is essential for genetic manipulation and recombinant protein production.

    Purpose of the Study:

    • To examine the mechanisms of nonconjugative plasmid replication and population-level maintenance.
    • To investigate plasmid persistence in Escherichia coli populations during growth.
    • To briefly consider strategies for enhancing recombinant product yields.

    Main Methods:

    • Focus on Escherichia coli as the model host organism.
    • Analysis of plasmid replication mechanisms at the single-cell level.

    Related Experiment Videos

  • Examination of plasmid maintenance strategies at the population level.

    • Main Results:

    • Detailed mechanisms of plasmid replication and segregation are elucidated.
    • Factors contributing to stable plasmid inheritance in growing bacterial populations are identified.
    • Strategies for optimizing recombinant gene expression are discussed.

    Conclusions:

    • The study provides insights into the molecular basis of plasmid stability in microbial communities.
    • Knowledge of these mechanisms can be applied to improve the efficiency of genetic engineering applications.
    • Effective plasmid maintenance is critical for the successful application of recombinant DNA technology.