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Combined central retinal artery-central vein obstruction
G C Brown1, J S Duker, R Lehman
1Retina Vascular Unit, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19118.
International Ophthalmology
|February 1, 1993
Summary
This study describes 23 patients with combined central retinal artery and vein obstruction, finding that 81% developed rubeosis iridis. Histopathology revealed retinal necrosis and periphlebitis.
Area of Science:
- Ophthalmology
- Retinal Vascular Diseases
Background:
- Combined central retinal artery and central retinal vein obstruction is a rare condition.
- Understanding its clinical presentation and complications is crucial for patient management.
Purpose of the Study:
- To describe the clinical characteristics, complications, and histopathological findings of unilateral combined central retinal artery-central retinal vein obstruction.
- To evaluate the incidence of rubeosis iridis in these patients.
Main Methods:
- Retrospective case series of 23 patients with unilateral combined central retinal artery-central retinal vein obstruction.
- Criteria included sudden visual loss, retinal whitening, cherry spot, and intraretinal hemorrhage.
- Follow-up data and histopathology were analyzed.
Main Results:
- 23 patients presented with unilateral combined central retinal artery-central retinal vein obstruction.
- Five cases (22%) occurred after retrobulbar injection.
- 81% of 21 patients with follow-up developed rubeosis iridis.
- Histopathology showed retinal necrosis and periphlebitis of the central retinal vein.
Conclusions:
- Combined central retinal artery-central retinal vein obstruction is associated with a high rate of rubeosis iridis.
- Retrobulbar injections may be a precipitating factor.
- Retinal necrosis and optic nerve periphlebitis are key histopathological findings.