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Updated: Aug 9, 2026

Single Molecule Analysis of Laser Localized Psoralen Adducts
Published on: April 20, 2017
Physical methods for the detection of carcinogen-DNA adducts in humans
1Molecular Epidemiology Section, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.
Abstract:
This report has attempted to summarize the principles, advantages, limitations and the source of data derived in the use of physical detection techniques for DNA-adduct measurement in human biomonitoring. Each method, although inherently chemically-specific, has advantages and limitations depending on the adduct type under study. These methods have a niche that is at least consistent with corroborative technology, and are being applied to dosimetry problems in the field.
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