Related Experiment Videos
Anaplastic astrocytoma with extracranial extension--case report
Neurologia Medico-Chirurgica
|May 1, 1993
Summary
This case study highlights a rare instance of malignant glioma extending outside the skull. Despite aggressive treatment, the patient succumbed to meningeal dissemination, underscoring the poor prognosis of such aggressive brain tumors.
Area of Science:
- Neuro-oncology
- Pathology
Background:
- Anaplastic astrocytoma is a malignant primary brain tumor.
- Skull base involvement and extracranial extension are uncommon presentations.
Observation:
- A 44-year-old female presented with anaplastic astrocytoma involving the right temporal lobe, skull base, and extending extracranially.
- Histological examination revealed astrocytoma with a desmoplastic reaction in the extracranial component.
Findings:
- The patient underwent subtotal tumor removal, radiation therapy, and chemotherapy.
- Despite treatment, the patient died due to meningeal dissemination of the tumor.
Implications:
- Spontaneous extradural extension of malignant glioma is an exceedingly rare event.
- This rare presentation carries a universally fatal outcome, emphasizing the aggressive nature of advanced gliomas.