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Clozapine-induced agranulocytosis and colony-stimulating cytokines
B M Ryabik1, V T Nguyen, R M Mann
1Department of Psychiatry and Behavioral Sciences, University of Louisville, School of Medicine, Kentucky.
General Hospital Psychiatry
|July 1, 1993
Abstract:
A case of clozapine-induced agranulocytosis that was treated with a granulocyte colony-stimulating cytokine is presented. The hematological status normalized. Two colony-stimulating factors are marketed for activating bone marrow function. Their utility in clozapine a granulocytoses is not clear, but they offer a potential new therapeutic option.