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[Immunoblotting analysis of acquired factor VIII inhibitor in an elderly man]
M Kikuchi1, M Sano, Y Shimamoto
1Department of Internal Medicine, Saga Medical School.
Abstract:
A case of acquired FVIII inhibitor in a nonhemophilic, 80 year-old man who had no underlying disorder, is presented. The level of inhibitor was 13.3 Bethesda unit/ml, and the antibody was IgG, with lambda light chain. The antibody reacted with the 92 kD fragment of non-treated human FVIII, and the 44 kD fragment of thrombin treated FVIII when analysed by the immunoblot analysis.