Related Experiment Videos
Effect of chronic ethanol administration on the absorptive functions of the rat small intestine
J Kaur1, V M Jaswal, J P Nagpaul
1Department of Biochemistry, Panjab University, Chandigarh, India.
Alcohol (Fayetteville, N.Y.)
|July 1, 1993
Abstract:
Ethanol feeding to rats for 40 days significantly (p < 0.01) depressed sodium-stimulated glucose and glycine uptakes at pH 5.5 and 7.2 without affecting sodium-independent solute transport in the rat intestine. Leucine uptake was essentially unaltered under these conditions. Absorption of bovine serum albumin and gamma-globulin as detected by enzyme-linked immunosorbent blocking assay (ELISA) was markedly augmented (p < 0.001) in ethanol-fed rats compared to the controls. These observations suggest that chronic ethanol intake differentially affects the uptake of organic solutes and macromolecules in the rat intestine.