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Numerical aberrations, including trisomy 22 as the sole anomaly, are recurrent in follicular thyroid adenomas
P Antonini1, N Lévy, B Caillou
1CNRS URA 1158, Laboratoire de Cytogénétique et Génétique Oncologiques, Institut Gustave-Roussy, Villejuif, France.
Genes, Chromosomes & Cancer
|September 1, 1993
Abstract:
Short-term cultures from 38 follicular thyroid adenomas revealed clonal numerical and/or structural chromosomal changes in 8 tumors, nonclonal changes in 1 tumor, and only normal karyotypes in 29 tumors. Three cases had trisomy 22 as the sole anomaly. Two cases had a combination of trisomies for chromosomes 5, 7, 9, 12, and 16.