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Congenital gingival granular cell tumor. A case report
O Günhan1, M Günhan, S Cetinkurşun
1Department of Pathology, Gülhane Military Medical Academy, Ankara, Turkey.
The Journal of Nihon University School of Dentistry
|June 1, 1993
Summary
Congenital gingival granular cell tumor is a rare newborn lesion. Immunohistochemistry suggests a mesenchymal cell origin for this benign tumor.
Area of Science:
- Oral pathology
- Developmental biology
- Histopathology
Background:
- Congenital gingival granular cell tumor (CGGCT) is an exceptionally rare benign oral lesion.
- This lesion exclusively affects newborn infants, with its etiology remaining largely unknown.
Observation:
- This report details a clinical case of a congenital gingival granular cell tumor in a neonate.
- The study involved a comprehensive immunohistochemical analysis of the tumor tissue.
Findings:
- Immunohistochemical markers including S-100 protein, epithelial membrane antigen (EMA), carcinoembryonic antigen (CEA), keratin, desmin, and vimentin were utilized.
- Results indicated the presence of markers consistent with a mesenchymal cell origin for the CGGCT.
Implications:
- The findings support the hypothesis that CGGCT arises from mesenchymal cells, contributing to our understanding of its pathogenesis.
- This research may aid in future diagnostic approaches and understanding of rare neonatal oral conditions.