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N-methyl-N-nitrosourea evidences cell cycle associated transient sequences in hepatic replicating DNA
1Department of Biochemistry and Molecular Biology, Faculty of Science, University of Bari, Italy.
Biochemical and Biophysical Research Communications
|March 17, 1995
Abstract:
Experiments of molecular hybridization were carried out with the aim of singling out DNA sequences which might be important in the hepatocarcinogenic action of N-methyl-N-nitrosourea. Results were obtained suggesting the synthesis of transitory DNA sequences during compensatory cell proliferation.