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Genetic and neurobiological basis of alcohol-seeking behavior
T K Li1, L Lumeng, W J McBride
1Indiana University School of Medicine, Indianapolis.
Alcohol and Alcoholism (Oxford, Oxfordshire)
|November 1, 1994
Abstract:
Through selective breeding, rat lines exhibiting high and low alcohol drinking preference have been developed as useful animal models for studying the neurobiological basis of alcohol-seeking behavior. The identified differences between lines in neurotransmitter functioning allows the evaluation of receptor agonist/antagonist compounds that might be efficacious in the treatment of alcohol craving and dependence.