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Immunoblotting analysis of somatic components of Dirofilaria immitis
M Hayasaki1, F Nanamura, K Konno
1Department of Internal Medicine and Parasitology, School of Veterinary Medicine, Tokyo University of Agriculture and Technology, Japan.
The Journal of Veterinary Medical Science
|December 1, 1994
Abstract:
SDS-PAGE analysis of Dirofilaria immitis extracts demonstrated the complexicity of protein components of microfilariae, similar to that of adult male and female worms. Immunoblotting analysis using sera from microfilaremic and amicrofilaremic dogs with D. immitis infection suggest that antigenic components in the low molecular weight region may be related to the anti-microfilarial mechanism of the host.