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Aortic valve replacement with autologous pericardium: surgical technique
1Department of Cardiovascular Diseases, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Journal of Cardiac Surgery
|January 1, 1995
Summary
This study details a novel aortic valve replacement using autologous pericardium, showing no hospital deaths or blood clots without anticoagulation. This technique is a promising option, especially for patients with small aortic annuli.
Area of Science:
- Cardiovascular Surgery
- Biomaterials Science
Background:
- Aortic valve replacement is a common cardiac procedure.
- Finding suitable materials for aortic valve prostheses is crucial for long-term patient outcomes.
- Autologous pericardium offers a potential biological alternative to synthetic valves.
Purpose of the Study:
- To describe a surgical technique for aortic valve replacement using freehand glutaraldehyde-treated autologous pericardium.
- To evaluate the early clinical outcomes and safety of this specific surgical approach.
Main Methods:
- A cohort of 49 patients underwent aortic valve replacement using the described freehand autologous pericardium technique.
- The procedure involved using glutaraldehyde-treated pericardial tissue fashioned into a valve.
- Follow-up assessments focused on mortality, thromboembolic events, and reoperation rates.
Main Results:
- The procedure demonstrated zero hospital mortality in the 49 patients.
- No thromboembolic episodes were observed, negating the need for anticoagulation.
- Three patients required reoperation due to infective endocarditis (two) or commissural tear (one).
Conclusions:
- The freehand glutaraldehyde-treated autologous pericardium technique for aortic valve replacement exhibits excellent hemodynamics.
- The low thrombogenicity of this method reduces the need for anticoagulation.
- This approach represents a viable alternative, particularly for patients with small aortic annuli.