Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pulmonary artery size after bidirectional cavopulmonary connection

D J Penny1, A Pawade, J L Wilkinson

  • 1Department of Cardiology, Royal Children's Hospital, Melbourne, Australia.

Journal of Cardiac Surgery
|January 1, 1995
PubMed
Summary

Bidirectional cavopulmonary connection (BCPC) surgery significantly reduces pulmonary artery size in patients. This suggests impaired pulmonary arterial growth after BCPC, potentially due to reduced blood flow or loss of artery expansion.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A simple, versatile valve model for use in lumped parameter and one-dimensional cardiovascular models.

International journal for numerical methods in biomedical engineering·2014
Same author

Paediatric heart transplantation in Australia comes of age: 21 years of experience in a national centre.

Internal medicine journal·2014
Same author

The c.7409G>A (p.Cys2470Tyr) Variant of FBN1: Phenotypic Variability across Three Generations.

Molecular syndromology·2013
Same author

Quantitative genetics and evolution: Is our understanding of genetics sufficient to explain evolution?

Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie·2011
Same author

Neonatal Tetanus in Sierra Leone.

British medical journal·2010
Same author

An investigation of bupropion substitution for the interoceptive stimulus effects of nicotine.

Journal of psychopharmacology (Oxford, England)·2009

Area of Science:

  • Cardiovascular Surgery
  • Pediatric Cardiology
  • Thoracic Imaging

Background:

  • Congenital heart defects often necessitate complex surgical interventions.
  • Bidirectional cavopulmonary connection (BCPC) is a palliative surgical procedure used in managing single-ventricle physiology.
  • Assessing the impact of BCPC on pulmonary artery development is crucial for long-term patient outcomes.

Purpose of the Study:

  • To evaluate changes in pulmonary arterial size following bidirectional cavopulmonary connection (BCPC).
  • To determine if BCPC affects the standardized growth of pulmonary arteries.
  • To explore potential mechanisms behind observed changes in pulmonary artery dimensions.

Main Methods:

  • Pulmonary arterial size was measured using cineangiography in 23 patients.

Related Experiment Videos

  • Measurements were taken preoperatively and postoperatively (1.9 months before and 14 months after BCPC).
  • Pulmonary artery size was standardized for body surface area using the pulmonary artery index (PAI).
  • Main Results:

    • A statistically significant reduction in the pulmonary artery index (PAI) was observed after BCPC.
    • The data indicate impaired growth of the pulmonary artery post-BCPC.
    • This reduction may be linked to decreased pulmonary arterial blood flow and/or diminished systolic expansion.

    Conclusions:

    • Bidirectional cavopulmonary connection (BCPC) is associated with a significant decrease in pulmonary artery size.
    • Pulmonary arterial growth appears to be impaired after BCPC surgery.
    • Further investigation is warranted to confirm the role of reduced flow and systolic expansion in this phenomenon.