Related Experiment Video
Updated: Aug 11, 2026
07:42
Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Inversion 14q in acute lymphoblastic leukemia of B-lineage
K F Wong1, Y L Kwong, T K Wong
1Department of Pathology, Queen Elizabeth Hospital, Kowloon, Hong Kong.
Cancer Genetics and Cytogenetics
|March 1, 1995
Abstract:
Many types of leukemia are associated with specific chromosomal rearrangements. Inversion 14(q11q32) has been reported to be specifically associated with post-thymic T-cell malignancies, including T-chronic lymphocytic leukemia. T-prolymphocytic leukemia, and adult T-cell leukemia/lymphoma. We have previously reported its occurrence in T-cell acute lymphoblastic leukemia. Recently, we encountered a case of acute lymphoblastic leukemia with inv(14)(q11q32), which surprisingly showed a B-cell immunophenotype (CD10+CD19+HLA-DR+Ig mu-).
