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Related Experiment Videos

Counter irritation test in primary fibromyalgia

R Guieu1, G Serratrice, J Pouget

  • 1URA CNRS 1455, Faculté de médecine secteur Nord, Marseille, France.

Clinical Rheumatology
|December 1, 1994
PubMed
Summary

Fibromyalgia patients experienced a significant decrease in pain reflex response when tender points were stimulated. This suggests a positive counter-irritation test could aid in diagnosing fibromyalgia.

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Area of Science:

  • Neuroscience
  • Pain Medicine
  • Rheumatology

Background:

  • Primary fibromyalgia is characterized by diffuse pain and tender points sensitive to palpation.
  • The diffuse noxious inhibitory system (DNIS) can be activated by
  • counter-irritation
  • stimulation.

Purpose of the Study:

  • To compare the effects of painful pressure on fibromyalgia tender points versus other body areas on the nociceptive flexion reflex (RIII reflex).
  • To investigate the potential of a counter-irritation test for diagnosing fibromyalgia.

Main Methods:

  • A study involving 18 fibromyalgia patients and 12 control subjects.
  • Application of painful pressure using a mechanical dolorimeter to tender points and control sites.
  • Measurement of the amplitude of the nociceptive flexion reflex of the lower limb (RIII reflex).

Main Results:

  • A significant decrease in RIII reflex amplitude was observed in 6 fibromyalgia patients during tender point stimulation.
  • This decrease indicates the activation of the diffuse noxious inhibitory control.

Conclusions:

  • The counter-irritation test, showing a decrease in RIII reflex amplitude, may serve as an objective diagnostic criterion for fibromyalgia.
  • Intense nociceptive stimulation is required to activate the diffuse noxious inhibitory control responsible for pain modulation.

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