Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cerebrovascular regulation and vasoneuronal coupling

M Daffertshofer1, M Hennerici

  • 1Department of Neurology, University of Heidelberg--Klinikum Mannheim, Germany.

Journal of Clinical Ultrasound : JCU
|February 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A consecutive and prospective stroke database covers the state of Baden-Wuerttemberg with 10.8 million inhabitants in Germany.

Neuroepidemiology·2013
Same author

Ultrasound emissions: thermal and mechanical indices.

Ultraschall in der Medizin (Stuttgart, Germany : 1980)·2013
Same author

Reduced diffusion in a subset of acute MS lesions: a serial multiparametric MRI study.

AJNR. American journal of neuroradiology·2012
Same author

Design, data management, and population baseline characteristics of the PERFORM magnetic resonance imaging project.

Journal of neurology·2010
Same author

White matter changes and diabetes predict cognitive decline in the elderly: the LADIS study.

Neurology·2010
Same author

[Consensus paper on peri-interventional and postinterventional stroke during cardiac catheter procedures].

Der Nervenarzt·2009

Transcranial Doppler sonography assesses cerebral blood flow velocity to evaluate cerebrovascular autoregulation and vasoneuronal coupling, aiding in the diagnosis of cerebral ischemia and monitoring neurological conditions.

Area of Science:

  • Neurology
  • Neurophysiology
  • Vascular Neurology

Background:

  • Cerebral perfusion pressure is vital for preventing cerebral ischemia.
  • Cerebrovascular autoregulation compensates for systemic pressure fluctuations.
  • Hypoperfusion arises from hemodynamic failure, autoregulation dysfunction, or both.

Purpose of the Study:

  • To evaluate the utility of transcranial Doppler sonography (TCD) in assessing cerebrovascular autoregulation and vasoneuronal coupling.
  • To investigate TCD's role in diagnosing conditions like orthostatic hypotension, arterial stenosis, and neurological disorders.

Main Methods:

  • Utilized TCD to measure cerebral blood flow velocity (CBFV).
  • Assessed CBFV during hypercapnia, vasoactive agent administration (acetazolamide), and tilt table examinations.

Related Experiment Videos

  • Monitored CBFV variations during neuronal stimulation to evaluate vasoneuronal coupling.

    • Main Results:

    • TCD effectively evaluates vasomotor regulation in patients with hemodynamic compromise.
    • Tilt table tests using TCD demonstrate cerebrovascular compensation or dysregulation in orthostatic hypotension.
    • CBFV changes during stimulation indicate vasoneuronal coupling integrity, with potential prognostic value in acute cerebral ischemia.

    Conclusions:

    • TCD is a valuable noninvasive tool for assessing cerebrovascular autoregulation and vasoneuronal coupling.
    • TCD aids in understanding the pathophysiology of cerebral hypoperfusion and neurological conditions.
    • Monitoring CBFV offers insights into cerebrovascular reserve and prognostic indicators for neurological deficits.