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Prepubertal gynecomastia during growth hormone therapy
1Division of Metabolism and Endocrine Drug Products, U.S. Food and Drug Administration, Rockville, Maryland 20857, USA.
The Journal of Pediatrics
|April 1, 1995
Abstract:
We report 22 cases of prepubertal gynecomastia diagnosed during growth hormone (GH) treatment. The age and dose range were 2 to 12 years and 0.18 [corrected] to 0.3 mg/kg per week, respectively. In most of the patients, gynecomastia appeared between 0.5 and 7 months after GH was started. Three boys were using drugs other than GH. This condition appears to be self-limited and benign.