N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea: a novel, high-affinity 5-HT2B receptor antagonist

Diurnal photosynthetic performance of two oak species from two provenances in a Mediterranean and a central European common garden.

Photosynthetica·2024

Integration of biochemical and topographic cues for the formation and spatial distribution of invadosomes in nasopharyngeal epithelial cells.

Acta biomaterialia·2019

Pyopericardium secondary to achalasia-associated squamous cell carcinoma of the oesophagus.

Annals of the Royal College of Surgeons of England·2016

Developing and assessing the utility of a You-Tube based clinical genetics video channel for families affected by inherited tumours.

Familial cancer·2016

Diversity and Community Composition of Vertebrates in Desert River Habitats.

PloS one·2015

Podoplanin mediates ECM degradation by squamous carcinoma cells through control of invadopodia stability.

Oncogene·2014

Structural and Mechanistic Studies of ADEPs Yield Potent Antibacterials and a Drug Formulation Strategy for Tuberculosis.

Journal of medicinal chemistry·2026

A 177Lu-Labeled Circular Bivalent Aptamer for PTK7-Targeting Radionuclide Therapy in Ovarian Cancer and Orthotopic Hepatoblastoma.

Journal of medicinal chemistry·2026

From Fragment Hit to Clinical Candidate: Discovery of Dual H1R/H4R Ligands with Superior Efficacy in Allergic Conjunctivitis.

Journal of medicinal chemistry·2026

Potent Anticancer Tethered Organorhodium(III) Complexes Target the Mitochondria.

Journal of medicinal chemistry·2026

Discovery of a Covalent NLRP3 LRR-Domain Probe: Reversing Renal Fibrosis via Immunometabolic Reprogramming in Organoid and Murine Models.

Journal of medicinal chemistry·2026

Lead Optimization of Multimutant KRAS Switch-II Pocket Macrocyclic Inhibitors via Isosteric Replacement to Improve ADME and Oral Exposure.

Journal of medicinal chemistry·2026

Structure-guided targeting of Plasmodium falciparum aminopeptidase P: exploiting S4' dimer-interface interactions for selective antimalarial drug design.

Expert opinion on therapeutic targets·2026

The quest to identify the molecular target of lithium.

Physical chemistry chemical physics : PCCP·2026

Design and syntheses of 4-aminoquinoline-thiazolidinone hybrids as anti-protozoal agents.

Frontiers in chemistry·2026

Computational screening of natural product inhibitor stargeting the MDM2-p53 interaction: docking and molecular dynamics insights for retinoblastoma therapy.

American journal of translational research·2026

Development and Molecular Evaluation of Novel 1,3-Disubstituted 1H-furo[2,3-c]pyrazol-4-ols: Synthesis, Characterization, ADMET, and Molecular Docking Studies.

Current organic synthesis·2026

Detecting Crystallization in Spray-dried Amorphous Solid Dispersion Tablets Administered in Apple Sauce: Feasibility, Challenges and Considerations.

AAPS PharmSciTech·2026

Related Experiment Videos

N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea: a novel, high-affinity 5-HT2B receptor antagonist

Related Concept Videos

Diurnal photosynthetic performance of two oak species from two provenances in a Mediterranean and a central European common garden.

Integration of biochemical and topographic cues for the formation and spatial distribution of invadosomes in nasopharyngeal epithelial cells.

Pyopericardium secondary to achalasia-associated squamous cell carcinoma of the oesophagus.

Developing and assessing the utility of a You-Tube based clinical genetics video channel for families affected by inherited tumours.

Diversity and Community Composition of Vertebrates in Desert River Habitats.

Podoplanin mediates ECM degradation by squamous carcinoma cells through control of invadopodia stability.

Structural and Mechanistic Studies of ADEPs Yield Potent Antibacterials and a Drug Formulation Strategy for Tuberculosis.

A 177Lu-Labeled Circular Bivalent Aptamer for PTK7-Targeting Radionuclide Therapy in Ovarian Cancer and Orthotopic Hepatoblastoma.

From Fragment Hit to Clinical Candidate: Discovery of Dual H1R/H4R Ligands with Superior Efficacy in Allergic Conjunctivitis.

Potent Anticancer Tethered Organorhodium(III) Complexes Target the Mitochondria.

Discovery of a Covalent NLRP3 LRR-Domain Probe: Reversing Renal Fibrosis via Immunometabolic Reprogramming in Organoid and Murine Models.

Lead Optimization of Multimutant KRAS Switch-II Pocket Macrocyclic Inhibitors via Isosteric Replacement to Improve ADME and Oral Exposure.

Structure-guided targeting of Plasmodium falciparum aminopeptidase P: exploiting S4' dimer-interface interactions for selective antimalarial drug design.

The quest to identify the molecular target of lithium.

Design and syntheses of 4-aminoquinoline-thiazolidinone hybrids as anti-protozoal agents.

Computational screening of natural product inhibitor stargeting the MDM2-p53 interaction: docking and molecular dynamics insights for retinoblastoma therapy.

Development and Molecular Evaluation of Novel 1,3-Disubstituted 1H-furo[2,3-c]pyrazol-4-ols: Synthesis, Characterization, ADMET, and Molecular Docking Studies.

Detecting Crystallization in Spray-dried Amorphous Solid Dispersion Tablets Administered in Apple Sauce: Feasibility, Challenges and Considerations.

Related Experiment Videos

N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea: a novel, high-affinity 5-HT2B receptor antagonist

Related Concept Videos

Related Articles