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[5-year experience with a central bone bank]

R L Deijkers1, S B Vehmeyer, M R Veen

  • 1Stichting BIS, Leiden.

Nederlands Tijdschrift Voor Geneeskunde
|March 25, 1995
PubMed
Summary
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The Leiden Bone Bank provides safe allogeneic bone and soft tissue for transplantation, adhering to international standards. Over five years, they distributed thousands of grafts with no known disease transmission, supporting various surgical specialties.

Area of Science:

  • Medical Science
  • Biotechnology
  • Tissue Engineering

Context:

  • Established in December 1988, the Leiden Bone Bank Foundation, in collaboration with the BIS Foundation, provides allogeneic bone and soft tissue for transplantation.
  • Bone banking has evolved into a sophisticated medical field governed by international standards to ensure the safety and efficacy of allografts.

Purpose:

  • To ensure the safe and effective provision of allogeneic bone and related soft tissue for transplantation.
  • To prevent disease transmission through rigorous donor selection and comprehensive laboratory testing.

Summary:

  • The Leiden Bone Bank distributed 450 deep-frozen massive bone allografts (221 osteoarticular and intercalary) and numerous soft tissue and bone grafts within its first five years.
  • Annual transplant numbers increased by at least 30%, with allografts utilized in orthopaedic, neurosurgery, and maxillofacial surgery.

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  • No infectious disease transmissions have been reported from grafts supplied by the Leiden Bone Bank.

    • Impact:

    • Facilitated a significant increase in allogeneic bone and soft tissue transplantation across multiple surgical disciplines.
    • Established a robust system for safe allograft procurement and distribution, contributing to patient care.
    • Demonstrated the successful implementation of international standards in bone banking, ensuring graft safety and efficacy.