Alzheimer's disease: a route to drug discovery

Hippocampal plasticity during the progression of Alzheimer's disease.

Neuroscience·2015

Isolation and characterization of human antibodies targeting human aspartyl (asparaginyl) beta-hydroxylase.

Human antibodies·2008

Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology.

Neuropathology and applied neurobiology·2007

PAN-811 (3-aminopyridine-2-carboxaldehyde thiosemicarbazone), a novel neuroprotectant, elicits its function in primary neuronal cultures by up-regulating Bcl-2 expression.

Neuroscience·2005

Tau epitope display in progressive supranuclear palsy and corticobasal degeneration.

Journal of neurocytology·2004

Inhibition of tau polymerization by its carboxy-terminal caspase cleavage fragment.

Biochemistry·2003

Physical function moderates the relationship between white matter characteristics and gait variability during uneven terrain walking in aging.

Neurobiology of aging·2026

Input-output curves demonstrate motor cortex hyperexcitability associated with cognitive impairment in Alzheimer's disease.

Neurobiology of aging·2026

Age-related differences in resting and event-evoked ocular response dynamics.

Neurobiology of aging·2026

Genetic architecture of Alzheimer's disease-related plasma biomarkers.

Neurobiology of aging·2026

The role of cognitive-motor interaction in landmark reliance and navigational deficits in older adults.

Neurobiology of aging·2026

Amyloid-associated cognitive trajectories in aging dogs mirror early changes in humans.

Neurobiology of aging·2026

A Sulfonamide Intermediate Elicits Therapeutic Effect Against Sepsis by Enhancing Neutrophil Maturation.

Journal of cellular and molecular medicine·2026

Herbicidal activity and mode-of-action of the natural product aureonitol isolated from Chaetomium coarctatum NEAU-Z3.

Pest management science·2026

Clofoctol-derived amphiphilic peptidomimetics exhibit broadened antimicrobial activity via multiple contributing mechanisms.

Journal of advanced research·2026

The black fly salivary protein Simukunin inhibits complement activation through the lectin pathway protease MASP-2.

The Journal of biological chemistry·2026

Penibrasdines A-E: Five cyclopiazonic acid-related indole alkaloids from the fungus Penicillium brasilianum.

Fitoterapia·2026

Neohesperidin and neohesperidin dihydrochalcone alleviated benzo[a]pyrene-induced toxicity: By inhibiting the activity of CYP1A1 enzyme.

Food chemistry·2026

Related Experiment Videos

Alzheimer's disease: a route to drug discovery

Related Concept Videos

Hippocampal plasticity during the progression of Alzheimer's disease.

Isolation and characterization of human antibodies targeting human aspartyl (asparaginyl) beta-hydroxylase.

Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology.

PAN-811 (3-aminopyridine-2-carboxaldehyde thiosemicarbazone), a novel neuroprotectant, elicits its function in primary neuronal cultures by up-regulating Bcl-2 expression.

Tau epitope display in progressive supranuclear palsy and corticobasal degeneration.

Inhibition of tau polymerization by its carboxy-terminal caspase cleavage fragment.

Physical function moderates the relationship between white matter characteristics and gait variability during uneven terrain walking in aging.

Input-output curves demonstrate motor cortex hyperexcitability associated with cognitive impairment in Alzheimer's disease.

Age-related differences in resting and event-evoked ocular response dynamics.

Genetic architecture of Alzheimer's disease-related plasma biomarkers.

The role of cognitive-motor interaction in landmark reliance and navigational deficits in older adults.

Amyloid-associated cognitive trajectories in aging dogs mirror early changes in humans.

A Sulfonamide Intermediate Elicits Therapeutic Effect Against Sepsis by Enhancing Neutrophil Maturation.

Herbicidal activity and mode-of-action of the natural product aureonitol isolated from Chaetomium coarctatum NEAU-Z3.

Clofoctol-derived amphiphilic peptidomimetics exhibit broadened antimicrobial activity via multiple contributing mechanisms.

The black fly salivary protein Simukunin inhibits complement activation through the lectin pathway protease MASP-2.

Penibrasdines A-E: Five cyclopiazonic acid-related indole alkaloids from the fungus Penicillium brasilianum.

Neohesperidin and neohesperidin dihydrochalcone alleviated benzo[a]pyrene-induced toxicity: By inhibiting the activity of CYP1A1 enzyme.

Related Experiment Videos

Alzheimer's disease: a route to drug discovery

Related Concept Videos

Related Articles