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In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears
Published on: February 21, 2018
Menière's disease. Etiologic considerations
1Emeritus Office, Cleveland Clinic Foundation, Ohio, USA.
Abstract:
This article explores the evidence for a common vascular pathophysiology for idiopathic Menière's disease and migraine. After retrospectively reviewing 85 cases of Menière's disease, it is concluded that (1) migraine occurs more often in patients with Menière's disease than in the general population, (2) the classic symptoms of Menière's disease can be part of a migraine attack, (3) symptoms of Menière's disease may be associated with a migraine attack without headache (migraine equivalent), (4) treatment for the migraine with methysergide maleate or prednisone may also improve the symptoms of Menière's disease, and (5) prospective studies with adequate follow-up are needed to further investigate this association.
Insights
Migraine is more common in Meniere's disease patients, with Meniere's symptoms potentially occurring during migraine attacks. Further research is needed to confirm this vascular pathophysiology link.
Area of Science:
- Neurology
- Vascular Medicine
Background:
- Idiopathic Meniere's disease and migraine are common neurological conditions.
- A potential shared vascular pathophysiology between these conditions warrants investigation.
Observation:
- Retrospective review of 85 Meniere's disease cases.
- Analysis of symptom overlap and treatment response.
Findings:
- Migraine prevalence is higher in Meniere's disease patients.
- Meniere's disease symptoms can manifest as part of a migraine attack or as a migraine equivalent.
- Migraine treatments (methysergide maleate, prednisone) may alleviate Meniere's symptoms.
Implications:
- Suggests a common vascular basis for Meniere's disease and migraine.
- Highlights the importance of considering migraine in Meniere's disease patients.
- Supports the need for prospective studies to validate the observed association.
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