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Updated: Aug 8, 2026

Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells
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The X inactivation centre and X chromosome imprinting

M F Lyon1

  • 1MRC Radiobiology Unit, Chilton, UK.

European Journal of Human Genetics : EJHG
|January 1, 1994
PubMed
Summary

Paternally inherited X chromosomes are preferentially inactivated in certain cell types, a process called genetic imprinting. Evidence suggests the Xist gene plays a key role in this X chromosome inactivation mechanism.

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