Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gynecomastia

A R Glass1

  • 1Endocrinology Service, Walter Reed Army Medical Center, Washington, DC.

Endocrinology and Metabolism Clinics of North America
|December 1, 1994
PubMed
Summary
This summary is machine-generated.

Gynecomastia, or male breast enlargement, often has no clear cause or is linked to puberty. Identifying and treating reversible factors like medications or underlying conditions is key for effective management.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bedside presentations and patients' perceptions of their medical care.

The New England journal of medicine·1997
Same author

Adrenal insufficiency in a man with non-classical 21-hydroxylase deficiency: consequence or coincidence?

Journal of endocrinological investigation·1994
Same author

Serum concentrations of insulin-like growth factor 1 in colonic neoplasia.

Acta oncologica (Stockholm, Sweden)·1994
Same author

Serum 25-hydroxyvitamin D concentrations in colonic neoplasia.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme·1993
Same author

Pharmaceutical advertising in the Journal.

The New England journal of medicine·1992
Same author

Serum gastrin is not higher in subjects with colonic neoplasia.

The American journal of gastroenterology·1992
Same journal

Navigating Adrenal Disease: A Comprehensive, Practical Guide for the Clinician.

Endocrinology and metabolism clinics of North America·2026
Same journal

Adrenal Disorders in Pregnancy.

Endocrinology and metabolism clinics of North America·2026
Same journal

Diagnosis and Management of Adrenocortical Carcinoma.

Endocrinology and metabolism clinics of North America·2026
Same journal

Pheochromocytomas and Paragangliomas.

Endocrinology and metabolism clinics of North America·2026
Same journal

Hereditary Conditions Associated with Adrenocortical Carcinoma, Pheochromocytoma, and Other Adrenal Tumors: Genetic Testing and Management Recommendations.

Endocrinology and metabolism clinics of North America·2026
Same journal

Primary Bilateral Macronodular Adrenal Hyperplasia.

Endocrinology and metabolism clinics of North America·2026
See all related articles

Area of Science:

  • Endocrinology
  • Men's Health
  • Oncology

Background:

  • Gynecomastia is a prevalent condition in men, frequently idiopathic or associated with puberty.
  • Medications, hypogonadism, neoplasms producing steroids/hCG, and systemic diseases (liver, renal, thyrotoxicosis) are potential causes.
  • The underlying mechanism often involves an elevated estrogen/androgen ratio impacting breast tissue.

Purpose of the Study:

  • To review the common and less common causes of gynecomastia.
  • To outline diagnostic considerations for male breast enlargement.
  • To discuss therapeutic strategies for managing gynecomastia.

Main Methods:

  • Literature review of causes and management of gynecomastia.
  • Analysis of hormonal imbalances and their role in breast tissue changes.

Related Experiment Videos

  • Evaluation of treatment efficacy for medical and surgical interventions.

    • Main Results:

    • Idiopathic causes and puberty are most common; medications are frequent culprits.
    • Neoplasms and systemic disorders necessitate specific diagnostic and treatment pathways.
    • An increased estrogen/androgen ratio is the primary driver in most cases.

    Conclusions:

    • Management focuses on addressing reversible causes, particularly medications and underlying disorders like tumors.
    • Medical therapies targeting the estrogen/androgen ratio, such as anti-estrogens, show some efficacy.
    • Surgical removal of excess tissue offers significant benefits, especially in younger individuals.