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Dinucleotide polymorphism at the DXS1178 locus is tightly linked to PGK1 at Xq13
R Fujita1, C Skolnick, A J Pakstis
1Department of Ophthalmology, Kellogg Eye Center, University of Michigan, Ann Arbor 48105, USA.
Human Genetics
|April 1, 1995
Abstract:
A polymorphic CA repeat (locus name DXS1178) was isolated from a 1-megabase YAC (OTCC) containing the OTC gene, located at Xp21.1. However, amplification in human-rodent hybrid cells and segregation analysis in three CEPH families mapped the DXS1178 locus at Xq13. The mapping ambiguity is apparently caused by the chimeric nature of the OTCC YAC clone.