Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Capillary pulse waveform in aortic stenosis

I R Mahy1, A C Shore, L D Smith

  • 1Department of Vascular Medicine, Postgraduate Medical School, University of Exeter, UK.

International Journal of Microcirculation, Clinical and Experimental
|September 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Meticillin-susceptible Staphylococcus aureus transmission among healthcare workers, patients and the environment in a large acute hospital under non-outbreak conditions investigated using whole-genome sequencing.

The Journal of hospital infection·2022
Same author

It's Not Over Till It's Over: A Prospective Cohort Study and Analysis of "Anesthesia Stat!" Emergency Calls in the Pediatric Post-Anesthesia Care Unit (PACU).

Cureus·2021
Same author

Meticillin-resistant Staphylococcus aureus transmission among healthcare workers, patients and the environment in a large acute hospital under non-outbreak conditions investigated using whole-genome sequencing.

The Journal of hospital infection·2021
Same author

The novel collagen matrikine, endotrophin, is associated with mortality and cardiovascular events in patients with atherosclerosis.

Journal of internal medicine·2021
Same author

Multiple distinct outbreaks of Panton-Valentine leucocidin-positive community-associated meticillin-resistant Staphylococcus aureus in Ireland investigated by whole-genome sequencing.

The Journal of hospital infection·2020
Same author

Renal nitrate clearance in chronic kidney disease.

Nitric oxide : biology and chemistry·2020
Same journal

Long-term registration of cutaneous microcirculation during general anesthesia.

International journal of microcirculation, clinical and experimental·1998
Same journal

Cardiovascular monitoring of elective aortic aneurysm repair using methods of chaos analysis.

International journal of microcirculation, clinical and experimental·1998
Same journal

Vascular smooth muscle, a multiply feedback-coupled system of high versatility, modulation and cell-signaling variability.

International journal of microcirculation, clinical and experimental·1998
Same journal

Synergetic interpretation of patterned vasomotor activity in microvascular perfusion: discrete effects of myogenic and neurogenic vasoconstriction as well as arterial and venous pressure fluctuations.

International journal of microcirculation, clinical and experimental·1998
Same journal

Is local metabolism the basis of the fractal vascular structure in the heart?

International journal of microcirculation, clinical and experimental·1998
Same journal

Reference sample microsphere method to measure blood flow effects on small intestinal perfusion in the rat.

International journal of microcirculation, clinical and experimental·1998
See all related articles

Peripheral microcirculation dynamics are crucial. Capillary pulse waveforms mirror central hemodynamics in aortic stenosis patients, despite local influences, but pulse wave transmission speed doesn

Area of Science:

  • Physiology
  • Cardiovascular Research
  • Microcirculation Dynamics

Background:

  • The dynamic nature of perfusion pressure in peripheral microcirculation is gaining recognition.
  • Capillary pressure is influenced by arterial inflow pressure and local/systemic factors affecting mean pressure and pulse waveform.
  • The impact of central pulse waveform changes on capillary pressure remains unclear.

Purpose of the Study:

  • To investigate the extent to which central pulse waveform changes influence capillary pressure.
  • To assess the detectability of central pulse waveform characteristics at the capillary level in human subjects.

Main Methods:

  • Utilized a dynamic capillary pressure measurement technique.
  • Studied human subjects diagnosed with aortic stenosis.

Related Experiment Videos

  • Analyzed capillary pulse waveform characteristics in relation to central hemodynamics.
  • Main Results:

    • Central pulse waveform characteristics typical of large vessels in aortic stenosis were detectable at the capillary level.
    • Local influences did not obscure the detection of these central waveform characteristics.
    • Changes in pulse wave transmission rate observed in large arteries were not evident at the microvascular level.

    Conclusions:

    • Capillary pulse waveform effectively mimics central hemodynamics in aortic stenosis.
    • Despite local factors, microcirculation reflects central hemodynamic patterns.
    • Pulse wave transmission dynamics differ between central arteries and microvasculature.