Related Experiment Video
Updated: Jul 31, 2026
Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection
Published on: July 25, 2017
Pathologist variation in reporting cervical borderline epithelial abnormalities and cervical intraepithelial
T Creagh1, J E Bridger, E Kupek
1Department of Histopathology and Cytopathology, St Mary's Hospital, London.
Aims:
To evaluate the interobserver variation in the diagnosis of cervical intraepithelial lesions, including the new category "borderline abnormalities of uncertain significance" (BAUS) which has not been tested before.
Methods:
Biopsy specimens of 122 patients were reviewed by five histopathologists and the diagnoses subjected to kappa statistical analysis.
Results:
There was poor interobserver agreement in all categories, particularly between BAUS and normal tissue.
Conclusions:
The current guidelines for the histological diagnosis of cervical intraepithelial neoplasia and BAUS are poorly reproducible.
