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[Quality of life analysis in patients treated for breast cancers]
B Zylberberg1, D Dormont, S Uzan
1Service de Gynécologie, Groupe Hospitalier Bichat-Claude-Bernard, Paris.
Objectives:
Evaluate the different quality of life parameters in treated breast cancer patients.
Type Of Study:
Retrospective analysis from 1977 to 1987.
Study Site:
Bichat, Lariboisière and Tenon Hospitals.
Patients:
239 operated patients, with or without irradiation following or before chemotherapy, with or without hormonotherapy. Patients were divided into 4 groups according to age. STUDY PARAMETERS: Essentially, gynaecologic consequences of treatments (flush, menstrual cycles, fertility, vaginal dryness, breast reconstruction), effect of tamoxifen on genital organs and osteopenia.
Main Results:
Tamoxifen acts as an oestrogen both on genital organs and bones.
Conclusion:
The impact of substitutive hormone therapy on quality of life should be evaluated in randomized studies.