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[Angiotrophic lymphoma in the paranasal sinuses]
K Kudo1, K Makishima, T Sugimoto
1Department of Otorhinolaryngology, University of Occupational and Environmental Health, School of Medicine, Kitakyushu.
Nihon Jibiinkoka Gakkai Kaiho
|February 1, 1995
Summary
Angiotrophic lymphoma, a rare B-cell malignancy, affects small blood vessels. Early diagnosis and chemotherapy, as seen in a paranasal sinus case, offer hope for recovery.
Area of Science:
- Oncology
- Pathology
- Hematology
Background:
- Angiotrophic lymphoma (neoplastic angioendotheliosis) is a rare neoplastic proliferation of B lymphocytes within small blood vessels.
- This condition can affect multiple organs, including the central nervous system, skin, lungs, kidneys, and adrenal glands.
Observation:
- A case report details a 78-year-old woman with bilateral occulomotor nerve paralysis presenting with paranasal sinus involvement.
- Initial diagnosis was pansinusitis, leading to ethmosphenoidectomy. Histopathological examination revealed angiotrophic lymphoma.
Findings:
- The patient received six courses of THP-COP chemotherapy, achieving successful remission.
- This case highlights the potential for angiotrophic lymphoma to manifest in the paranasal sinuses.
Implications:
- Angiotrophic lymphoma may be underdiagnosed due to its varied presentations and rarity.
- Prompt diagnosis and treatment, including chemotherapy, are crucial for favorable outcomes in angiotrophic lymphoma.