[Defence system of gastroduodenal mucous glands in ulcer disease]

As a result of complex investigation of the dafence mucosal barrier of gastroduodenal zone (studying of glicoproteins and immunoglobulins secretion), the acid-producing stomach function and its colonization with helicobacter pylori bacteria it was determined that side by side with infringement of polysaccharide-albuminous complexes secretion the weakening of humoral and nonspecific local immunity occurs. The infringement degree depends on severity of ulcer disease. On the background of autoimmune aggression the stress in common immunity system was noted. The presence of helicobacteria negatively influences the state of defence mucosal barrier.