Callitrichid IgM-nephropathy--an old age-related disease?
Related Experiment Video
Updated: Oct 9, 2026

Detection of MicroRNA Expression in the Kidneys of Immunoglobulin A Nephropathic Mice
Published on: July 8, 2020
1Deutsches Primatenzentrum GmbH, Göttingen, Germany.
Abstract:
In 185 callitrichids of exactly known age the occurrence of mesangial IgM-deposits and mesangial lesions has been evaluated. Mesangial IgM-deposits were observed already in early infancy, at that time without morphological sequelae. Signs of mesangial lesions were first observed in a 3-months old animal and with a sharp increase of mesangial lesions between 4 months and one year of age all suggesting an onset early in life. In contrast in higher age groups a significant number of animals suffered from glomerulosclerosis without IgM deposits, which could be interpreted as 'old age nephropathy' independent from IgM-nephropathy.
More Related Videos
14:18Dioscin Mediated IgA Nephropathy Alleviation by Inhibiting B Cell Activation In Vivo and Decreasing Galactose-Deficient IgA1 Production In Vitro
Published on: October 13, 2023
07:15Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
Published on: August 23, 2024
Related Concept Videos
Nephrons
Nephrotic Syndrome I : Introduction
Chronic Kidney Disease I: Introduction
Chronic Kidney Disease II: Clinical Manifestations
Chronic Kidney Disease III: Interprofessional Care
Diabetic Nephropathy