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Related Experiment Videos

Management outcome for multiple intracranial aneurysms

J Rinne1, J Hernesniemi, M Niskanen

  • 1Department of Neurosurgery, University Hospital of Kuopio, Finland.

Neurosurgery
|January 1, 1995
PubMed
Summary

Patients with multiple intracranial aneurysms (MIA) face poorer outcomes and higher mortality compared to those with single intracranial aneurysms (SIA). Delayed neurological deficits significantly impact MIA patient outcomes.

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Area of Science:

  • Neurosurgery
  • Neurology
  • Vascular Neurology

Background:

  • Multiple intracranial aneurysms (MIA) present unique management challenges.
  • Outcomes for MIA patients are less understood compared to single intracranial aneurysms (SIA).

Purpose of the Study:

  • To assess and compare the management outcomes of patients with MIA versus SIA.
  • To identify factors influencing outcomes in MIA patients.

Main Methods:

  • Retrospective analysis of 302 MIA patients from a cohort of 1314 cerebral aneurysm cases.
  • Glasgow Outcome Scale used for 1-year follow-up assessment.
  • Multivariate analysis to determine independent predictors of outcome.

Main Results:

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  • MIA patients demonstrated significantly poorer outcomes and higher mortality rates than SIA patients.
  • Poor outcomes were more pronounced in MIA patients with Hunt and Hess Grades 2-3.
  • Delayed neurological deficit was the most significant independent predictor of poor outcome in MIA patients.

    • Conclusions:

    • MIA management is associated with worse outcomes and higher mortality than SIA.
    • Delayed neurological deficits are critical factors affecting MIA patient prognosis.
    • Further research into optimizing MIA treatment strategies is warranted.