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[Results of electroencephalographic tests in children with bronchial asthma]
C Zychowicz1, I Czubkowska, T Kmieć
1Oddziału Alergologii i Chorób Infekcyjnych CZD.
Insights
This study found that over half of children hospitalized for asthma showed abnormal EEG results, indicating potential central nervous system damage from hypoxia. These findings highlight the neurological impact of severe asthma in pediatric patients.
Area of Science:
- Neurology
- Pediatrics
- Pulmonology
Background:
- Bronchial asthma is a common respiratory condition in children.
- Severe or persistent asthma can lead to recurrent hypoxia.
- The impact of hypoxia on the developing central nervous system (CNS) requires further investigation.
Purpose of the Study:
- To investigate the prevalence of central nervous system abnormalities in children hospitalized with bronchial asthma.
- To assess the correlation between asthma severity, disease duration, hypoxia episodes, and neurological findings.
Main Methods:
- Electroencephalogram (EEG) examinations were conducted on 100 children (aged 2-18) hospitalized for moderate to severe bronchial asthma.
- Children underwent two EEG assessments during treatment, including euphylline administration.
- EEG results were analyzed based on the presence and type of electrical discharges.
Main Results:
- Abnormal EEG records were observed in 52% of the children studied.
- Generalized paroxysmal discharges were noted in 16 children, primarily those with severe asthma.
- Generalized and focal EEG changes were found in 12% and 23% of children, respectively.
- More significant EEG abnormalities were associated with asthma duration exceeding five years and a history of unconsciousness.
Conclusions:
- Recurrent hypoxia associated with bronchial asthma frequently leads to central nervous system damage in children.
- EEG abnormalities are common in pediatric patients with moderate to severe asthma.
- These findings underscore the importance of monitoring neurological health in children with severe or chronic asthma.
Abstract:
In the years 1988-1990, 100 children aged from 2 to 18 years were examined, who were hospitalized for bronchial asthma of moderately severe and severe clinical course. In all children the examinations were performed twice at intervals of several weeks or several months during administration of the full set of drugs, including euphylline. The results were estimated according to the number and character of electric discharges. Out of the total number of 100 children in 52 cases abnormal EEG record was found. Generalized paroxysmal discharges were found in 16 children mainly with severe and moderately severe course of asthma. Generalized changes were recorded in 12 children mainly with moderately severe course of the disease. Milder focal changes were found in 23 children. Most evident changes occurred in children with over five years of disease duration and with history of unconsciousness episodes. The studies carried out indicate a relatively frequent, that is in half the cases, damage to the central nervous system following repeated episodes of hypoxia.
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