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Updated: Aug 11, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
[Epilepsy as a complication of bronchial asthma]
I Czubkowska1, B Karkowska, E Najberg
1Oddziału Alergologii i Chorób Infekcyjnych, Oddiału Neurologii Dzieciecej Pomnika Szpitala Centrum Zdrowia Dziecka w Warszawie.
Insights
Severe asthma attacks in children can lead to epilepsy. Prompt asthma treatment is crucial for preventing seizures and neurological complications in pediatric patients.
Area of Science:
- Pediatric Neurology
- Allergy and Immunology
Context:
- Bronchial asthma is a common respiratory condition in children.
- Severe asthma exacerbations can have significant systemic implications.
Purpose:
- To investigate the co-occurrence of epilepsy in children with severe bronchial asthma.
- To explore the relationship between asthma severity and seizure disorders.
Summary:
- Epilepsy was diagnosed in 9 out of 120 pediatric patients (7-15 years) hospitalized for severe asthma.
- Grand mal seizures were observed in 8 patients, with seizures occurring during both acute asthma and recovery phases.
- Electroencephalogram (EEG) abnormalities were noted in 22 of 29 examinations.
Impact:
- Severe, prolonged asthma attacks may precipitate epilepsy in susceptible children.
- Antiasthmatic therapies showed no adverse central nervous system effects.
- Effective asthma management is proposed as a key preventive strategy for epilepsy in this population.
Unlabelled:
Epilepsy was recognized in 9 of 120 patients with bronchial asthma, aged 7-15 years, hospitalized in the Department of Allergology and Infectious Diseases in the Years 1989-1992. All the children had severe asthma attacks previously, six of them required hospitalisation at Intensive Care Unit. In 8 of the patients grand mal (generalised, tonic-clonic) seizures was observed, one child had absence state. Seizures were present both in the acute state of the asthma and during improvement. Anticonvulsant therapy was started immediately after diagnosis of epilepsy has been established. Clinical improvement with cease of seizures was noted there after. All the 9 patients had EEG examinations: 22 out of 29 performed, were abnormal.
Conclusions:
1. Severe asthma attacks lasting for a considerable period of time, mainly 5 years, evoke epilepsy. 2. Undesirable signs of the antiasthmatic therapy on CNS was not found. 3. Accurate treatment of asthma seems to be the best prophylaxis of epilepsy.
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