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Raymond's syndrome following petrosal sinus sampling
H Seyer1, J Honegger, W Schott
1Department of Neurosurgery, University of Erlangen-Nürnberg, Federal Republic of Germany.
Acta Neurochirurgica
|January 1, 1994
Summary
Inferior petrosal sinus sampling (IPSS) can help diagnose Cushing's disease. However, a rare but serious complication of brain stem ischemia highlights the need to carefully consider its use.
Area of Science:
- Endocrinology
- Neurology
- Neurosurgery
Background:
- Inferior petrosal sinus sampling (IPSS) is a diagnostic procedure to confirm pituitary-dependent Cushing's disease.
- It aids in localizing microadenomas before transsphenoidal surgery.
Observation:
- A 14-year-old boy experienced a severe complication following IPSS.
- The complication involved brain stem ischemia, leading to abducens nerve palsy and hemiparesis (Raymond's syndrome).
Findings:
- This case highlights a rare but significant risk associated with IPSS.
- The event underscores the potential for serious neurological complications.
Implications:
- The findings necessitate a re-evaluation of the indications for performing IPSS.
- Risk-benefit assessment is crucial when considering this invasive diagnostic procedure for Cushing's disease.