Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Retinoma associated with vitreous seeding

G T Lueder1, E Héon, B L Gallie

  • 1Department of Ophthalmology, Washington University Medical Center, St. Louis, MO 63110, USA.

American Journal of Ophthalmology
|April 1, 1995
PubMed
Summary

Vitreous seeding in retinoma, a rare condition, does not necessarily indicate malignant transformation to retinoblastoma. Long-term follow-up of two patients showed stable lesions without cancerous changes, suggesting a benign prognosis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

DNA hypermethylation/boundary control loss identified in retinoblastomas associated with genetic and epigenetic inactivation of the <i>RB1</i> gene promoter.

Epigenetics·2020
Same author

IFT80 mutations cause a novel complex ciliopathy phenotype with retinal degeneration.

Clinical genetics·2018
Same author

Novel retinal findings in peroxisomal biogenesis disorders.

Ophthalmic genetics·2018
Same author

Specific retinal phenotype in early IQCB1-related disease.

Eye (London, England)·2017
Same author

The combination of vestibular impairment and congenital sensorineural hearing loss predisposes patients to ocular anomalies, including Usher syndrome.

Clinical genetics·2016
Same author

Liver anomalies as a phenotype parameter of Bardet-Biedl syndrome.

Clinical genetics·2015

Area of Science:

  • Ophthalmology
  • Oncology

Background:

  • Retinoma is a benign retinal tumor.
  • Malignant transformation to retinoblastoma is rare but concerning.
  • Vitreous seeding is a potential indicator of aggressive disease.

Observation:

  • Two patients with retinoma and vitreous seeding were monitored.
  • Follow-up periods were 8 years and 33 years.
  • No malignant transformation to retinoblastoma was observed.

Findings:

  • Vitreous seeding in retinoma did not lead to malignant transformation in these cases.
  • The retinoma lesions remained stable over extended follow-up periods.
  • This suggests vitreous seeding alone is not a definitive sign of malignancy.

Implications:

Related Experiment Videos

  • Vitreous seeding in retinoma may not warrant aggressive treatment.
  • Further research is needed to understand the prognostic significance of vitreous seeding.
  • This finding can help refine clinical management strategies for retinoma patients.