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Mapping using human blood composition data
L I Zhuk1, I N Mikholskaya, E A Danilova
1Institute of Nuclear Physics Tashkent, Ulughbek, Uzbekistan, CIS.
Biological Trace Element Research
|January 1, 1994
Summary
Elemental composition in human blood and hair was mapped in Uzbekistan using instrumental neutron activation analysis (INAA). Results revealed correlations between elemental levels and diseases, with blood showing occupational variations and hair indicating regional contamination.
Area of Science:
- Environmental Science
- Human Health
- Analytical Chemistry
Background:
- Elemental composition in biological samples is crucial for understanding human health.
- Instrumental neutron activation analysis (INAA) is a powerful technique for elemental mapping.
- Regional environmental factors and occupational exposures can influence elemental concentrations.
Purpose of the Study:
- To map the elemental composition of whole blood and hair in Uzbekistan.
- To investigate correlations between elemental concentrations and regional medical statistics.
- To compare the utility of blood and hair elemental analysis for assessing regional contamination and occupational exposures.
Main Methods:
- Instrumental Neutron Activation Analysis (INAA) was employed.
- Analysis of 2500 whole blood samples and hair samples.
- Determination of average concentrations for 15 elements in blood and 24 elements in hair.
Main Results:
- Correlations between elemental concentrations and various diseases were identified.
- Human hair composition showed greater sensitivity to regional contamination compared to blood.
- Specific occupational groups exhibited distinct changes in blood elemental composition.
Conclusions:
- Elemental analysis of hair is a valuable indicator of regional environmental contamination.
- Blood elemental analysis can reveal specific health impacts related to occupational exposures.
- Both blood and hair elemental profiles provide complementary insights into human health and environmental exposure.