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cDNA encoding a chicken protein (CRP1) with homology to hnRNP type A/B
A Cvekl1, J B McDermott, J Piatigorsky
1Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892-2730, USA.
Abstract:
The sequence of a cDNA encoding a putative chicken RNA-binding protein is reported. The C-terminal portion of the predicted protein is similar to a family of nucleic acid binding proteins that includes murine CArG box-binding factor CBF-A, human hnRNP A/B, hepatitis B enhancer-binding protein E2BP, and AU-rich RNA-binding protein AUF1. These proteins all have two consecutive RNA recognition motifs. However, the N-terminal 72 amino acids of this deduced chicken protein show no relation to the N-terminal sequences of the other proteins. We call this protein chicken ribonucleoprotein, CRP1.
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