Total intravenous anesthesia with propofol vs. propofol/midazolam in oncology patients

The goal of this study was to determine dose requirements of propofol vs. propofol/midazolam in oncology patients during total intravenous anesthesia. The design of the study was a controlled clinical trial. The setting was the Oncology Hospital, National Medical Center, IMSS, located in Mexico City. Sixty patients were allocated randomly into two groups, patients in control group received propofol and fentanyl to induced and to maintain the anesthesia. Twenty nine patients in the experimental group received propofol and midazolam to induce anesthesia and to maintain propofol and fentanyl. The combination of propofol and midazolam to induce general anesthesia in oncology patients reduced the requirements in propofol and fentanyl in total intravenous anesthesia.