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Stimulation of penetrating corneal wound healing by exogenous fibronectin
R A Gundorova1, I V Brikman, S I Ibadova
1Moscow Helmholtz Research Institute of Eye Diseases, Russia.
European Journal of Ophthalmology
|October 1, 1994
Abstract:
The paper describes the effect of exogenous fibronectin administered by instillation on the repair of the rabbit cornea after experimental mechanical injury. The effect was monitored by light microscopy and radioautography. Fibronectin had a beneficial effect on regenerating corneal epithelium, endothelium and keratocytes through a stimulatory effect on cell migration, proliferation and differentiation.