Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Respiratory Failure-I01:21

Acute Respiratory Failure-I

883
Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
883
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

470
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
470
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

801
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
801
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

1.0K
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
1.0K
Acute Respiratory Failure-IV01:23

Acute Respiratory Failure-IV

521
Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
521
Respiratory Assessment: Purpose and Indications01:19

Respiratory Assessment: Purpose and Indications

1.7K
Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dietary habits affect fatty acid composition of visceral adipose tissue in subjects with colorectal cancer or obesity.

European journal of nutrition·2019
Same author

The pre-mir-27a variant rs895819 may contribute to type 2 diabetes mellitus susceptibility in an Iranian cohort.

Journal of endocrinological investigation·2016
Same author

Oral glucose tolerance test unravels circulating miRNAs associated with insulin resistance in obese preschoolers.

Pediatric obesity·2016
Same author

Evaluating the association of common UBE2Z variants with coronary artery disease in an Iranian population.

Cellular and molecular biology (Noisy-le-Grand, France)·2015
Same author

Depigmentation therapy in vitiligo universalis with cryotherapy and 4-hydroxyanisole.

Clinical and experimental dermatology·2010
Same author

[Endocrine disruptors -- Monograph. 3. Arsenic].

Giornale italiano di medicina del lavoro ed ergonomia·2009
Same journal

Preventable yet persistent: silicosis and gaps in public health policy - a narrative review.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
Same journal

Takotsubo syndrome due to occupational stress in a physician.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
Same journal

Spirometry after treatment completion for pulmonary tuberculosis - a necessity?

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
Same journal

Heart failure at the crossroads of climate change and environmental health: emerging risks, mechanistic insights, and future directions.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
Same journal

Aspiration pneumonia in stroke survivors: prevalence and clinical associations at Bolan Medical Complex.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
Same journal

The silent fractures: unmasking osteoporosis in south Indian chronic obstructive pulmonary disease patients.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
See all related articles

Related Experiment Video

Updated: Jan 19, 2026

Author Spotlight: Exploring Venous Waveforms for Non-Invasive Respiratory Monitoring in Pigs
04:10

Author Spotlight: Exploring Venous Waveforms for Non-Invasive Respiratory Monitoring in Pigs

Published on: March 8, 2024

1.8K

Acute respiratory failure

R Poggi1, A Masotti, A Rossi

  • 1Divisione di Pneumologia, Ospedale Maggiore di Borgo Trento, U.L.S.S. 25, Verona, Italia.

Monaldi Archives for Chest Disease = Archivio Monaldi Per Le Malattie Del Torace
|December 1, 1994
PubMed
Summary
This summary is machine-generated.

Respiratory failure impairs gas exchange, requiring mechanical ventilation. Innovative mask ventilation techniques aim to prevent complications associated with tracheal intubation, improving patient outcomes in critical care.

More Related Videos

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
06:22

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS

Published on: April 7, 2021

3.8K
A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation
07:40

A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation

Published on: August 30, 2019

9.4K

Related Experiment Videos

Last Updated: Jan 19, 2026

Author Spotlight: Exploring Venous Waveforms for Non-Invasive Respiratory Monitoring in Pigs
04:10

Author Spotlight: Exploring Venous Waveforms for Non-Invasive Respiratory Monitoring in Pigs

Published on: March 8, 2024

1.8K
Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
06:22

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS

Published on: April 7, 2021

3.8K
A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation
07:40

A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation

Published on: August 30, 2019

9.4K

Area of Science:

  • Pulmonology
  • Critical Care Medicine
  • Respiratory Physiology

Background:

  • Respiratory failure is a critical impairment of gas exchange due to lung or pump failure, leading to hypoxemia or hypercapnia.
  • It can be acute (e.g., acute lung injury, asthma) or acute on chronic (e.g., COPD, chest wall disorders).
  • Mechanical ventilation is a life-saving treatment for critically ill patients but carries risks like infection and barotrauma.

Purpose of the Study:

  • To discuss the critical role of mechanical ventilation in managing respiratory failure.
  • To highlight the complications associated with traditional mechanical ventilation.
  • To introduce and emphasize the benefits of innovative ventilation techniques like mask ventilation and proportional assist ventilation (PAV).

Main Methods:

  • Review of existing literature on respiratory failure and mechanical ventilation.
  • Discussion of acute and acute on chronic respiratory failure classifications.
  • Exploration of alternative ventilation strategies, focusing on mask ventilation.

Main Results:

  • Mechanical ventilation is essential but associated with significant complications.
  • Mask ventilation and PAV offer alternative approaches to respiratory support.
  • Mask ventilation aims to mitigate risks linked to tracheal intubation, such as infections and barotrauma.

Conclusions:

  • Respiratory failure necessitates advanced respiratory support.
  • Innovative ventilation methods, particularly mask ventilation, present a promising strategy to reduce complications.
  • Further research into mask ventilation is warranted for critical care settings.