Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple organ dysfunction after heart valve replacement

D Wang1, L Zhu, G Li

  • 1General Hospital of PLA, Beijing.

Chinese Medical Journal
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Encapsulation of plasmid DNA in biodegradable poly(D, L-lactic-co-glycolic acid) microspheres as a novel approach for immunogene delivery.

Journal of controlled release : official journal of the Controlled Release Society·1998
Same author

Identification of two Escherichia coli pseudouridine synthases that show multisite specificity for 23S RNA.

Biochemistry·1998
Same author

Chemosignal transduction in the vomeronasal organ of garter snakes: cloning of a gene encoding adenylate cyclase from the vomeronasal organ of garter snakes.

Archives of biochemistry and biophysics·1998
Same author

Inhibitory activity of unsaturated fatty acids and anacardic acids toward soluble tissue factor-factor VIIa complex.

Journal of natural products·1998
Same author

A new member of the mouse prolactin (PRL)-like protein-C subfamily, PRL-like protein-C alpha: structure and expression.

Endocrinology·1998
Same author

Pharmacokinetics and biodistribution of radioimmunoconjugates of anti-CD19 antibody and single-chain Fv for treatment of human B-cell malignancy.

Cancer immunology, immunotherapy : CII·1998
Same journal

Chronic kidney disease in women: Global trends and metabolic-cardiovascular associations.

Chinese medical journal·2026
Same journal

Uptake and associated factors of breast cancer screening using mammography and ultrasound in China: A multicenter population-based study.

Chinese medical journal·2026
Same journal

Oncogenic DNMT3B as a therapeutic target for cervical cancer.

Chinese medical journal·2026
Same journal

Age of onset by temporal and spatial changes and prognostic value for esophageal cancer.

Chinese medical journal·2026
Same journal

Secular trends in society-, school-, and individual-level factors related to physical activity and their associations with elevated blood pressure among 0.6 million children and adolescents.

Chinese medical journal·2026
Same journal

Role of incretins in Alzheimer's disease and their impact on behavioral aspects.

Chinese medical journal·2026
See all related articles

Multiple organ dysfunction (MOD) after valve replacement is a serious complication. Preventing pulmonary infection is crucial for patient survival, alongside managing heart and lung function.

Area of Science:

  • Cardiology
  • Critical Care Medicine
  • Thoracic Surgery

Background:

  • Multiple organ dysfunction (MOD) is a significant concern following cardiac valve replacement surgery.
  • The study examines the incidence and mortality associated with MOD in patients undergoing valve replacement between 1980 and 1991.

Purpose of the Study:

  • To investigate the incidence and mortality of multiple organ dysfunction (MOD) after valve replacement.
  • To analyze the clinical types and predisposing factors of severe MOD (dysfunction of more than 3 organs).
  • To emphasize the importance of preventing pulmonary infection in managing MOD.

Main Methods:

  • Retrospective analysis of patient data from 1980-1991.
  • Categorization of MOD into acute, deteriorating, and pulmonary infection types.

Related Experiment Videos

  • Identification of predisposing and triggering factors for MOD.

    • Main Results:

    • Incidences of MOD involving 2, 3, and 4 organs were 17.1%, 5.6%, and 4.3%, respectively.
    • Mortality rates for 2, 3, and 4 organ MOD were 12%, 18.5%, and 76.2%.
    • Acute pump failure and hypoxemia are primary predisposing factors, with infection (especially pulmonary) as a key trigger.

    Conclusions:

    • Severe MOD is a critical complication after valve replacement with high mortality.
    • Pulmonary infection plays a vital role in the progression and outcome of MOD.
    • Preventing pulmonary infection is as critical as managing cardiac and respiratory function post-surgery.