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High flow priapism associated with sickle cell disease
C E Ramos1, J S Park, M L Ritchey
1Department of Surgery (Division of Urology), University of Texas Medical School, Houston 77030, USA.
The Journal of Urology
|May 1, 1995
Summary
High flow priapism, a rare condition in sickle cell disease patients, challenges the typical low-flow understanding. This study presents two cases, highlighting a potential new presentation of priapism in sickle cell disease.
Area of Science:
- Urology
- Hematology
- Vascular Surgery
Background:
- Priapism in sickle cell disease is typically a low-flow condition.
- High-flow priapism is predominantly associated with penile trauma and cavernous artery injury.
Observation:
- Two cases of sickle cell disease patients presenting with high-flow priapism were observed.
- Neither patient had evidence of penile vascular trauma on clinical or radiographic assessment.
Findings:
- One patient received unsuccessful treatment with intracorporeal methylene blue injection.
- Successful treatment was achieved in one patient via bilateral pudendal artery embolization.
Implications:
- The findings suggest a non-traumatic etiology for high-flow priapism in sickle cell disease.
- Further research is needed to elucidate the underlying pathophysiological mechanisms.