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[Hypoplastic leukemia achieved long-term remission with low-dose cytosine arabinoside]
S Fujisawa1, H Kanamori, T Noguchi
1Department of Hematology and Chemotherapy, Kanagawa Cancer Center.
[Rinsho Ketsueki] the Japanese Journal of Clinical Hematology
|January 1, 1995
Abstract:
A 74-year-old woman was admitted in October 1988 with anemia and leukocytopenia. Hematologic investigations established a diagnosis of hypoplastic acute leukemia. She received a low dose of cytosine arabinoside (LDAC: 10 mg/m2 every 12 hours) subcutaneously for 21 days and achieved complete remission (CR) one month later. After one course of LDAC of 14 days, she received LDAC of 21 days every 5 to 6 months as maintenance therapy till April 1993. She has been in remission for 6 years. Intensification therapy with LDAC every 5 to 6 months might be useful in maintaining remission for hypoplastic acute leukemia.