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Sleep apnoea and nocturnal angina
K A Franklin1, J B Nilsson, C Sahlin
1Department of Pulmonary Medicine and Allergology, University Hospital of Northern Sweden, Umeå.
Lancet (London, England)
|April 29, 1995
Summary
Sleep apnoea causes hypoxaemia, potentially leading to nocturnal angina. Treating sleep apnoea with continuous positive airway-pressure reduced nocturnal angina and myocardial ischaemic events.
Area of Science:
- Cardiology
- Sleep Medicine
- Respiratory Medicine
Background:
- Sleep apnoea is frequently associated with hypoxaemia.
- Hypoxaemia during sleep may precipitate nocturnal angina.
- Nocturnal angina pectoris is a concerning symptom of cardiac ischaemia.
Purpose of the Study:
- To investigate the link between sleep apnoea and nocturnal angina.
- To evaluate the efficacy of continuous positive airway-pressure (CPAP) in managing nocturnal angina in patients with sleep apnoea.
Main Methods:
- Observational study of patients with nocturnal angina.
- Diagnosis of sleep apnoea using standard methods.
- Treatment of sleep apnoea with continuous positive airway-pressure.
- Assessment of nocturnal angina symptoms and myocardial ischaemic events via vector-cardiography.
Main Results:
- Sleep apnoea was identified in 9 out of 10 patients presenting with nocturnal angina.
- Continuous positive airway-pressure treatment led to a significant reduction in nocturnal angina episodes.
- Computerised vector-cardiography confirmed a decrease in nocturnal myocardial ischaemic events following CPAP therapy.
Conclusions:
- Sleep apnoea is a prevalent comorbidity in patients with nocturnal angina.
- Effective treatment of sleep apnoea with CPAP can alleviate nocturnal angina and reduce cardiac ischaemia.
- Addressing sleep-disordered breathing is crucial for managing patients with refractory nocturnal angina.