A spreadsheet technique for dosimetry of transperineal prostate implants

Although conceptually straightforward, dosimetry of permanent 125I seed prostate implants is not necessarily easy to implement in clinical practice, especially for institutions that are unwilling or unable to modify their commercial RTP systems. Spreadsheet techniques that aid in both preimplant treatment planning and post-implant dosimetric evaluation have been developed. The first spreadsheet converts the seed distribution expressed in terms of template grid coordinates to the format suitable for input into the RTP system, and determines the positions and loading patterns of individual needles. The second spreadsheet macroprogram is designed, as a modification of the Roy et al. [Int. J. Radiat. Oncol. Biol. Phys. 26, 163-169 (1993)] technique, to interactively determine physical seed locations from the post-implant CT images. Although less automated than described elsewhere, this approach was found acceptable for clinical practice at our institution.