Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antidepressants and overdoses

J A Henry1

  • 1National Poisons Unit, Guy's Hospital, London.

Postgraduate Medical Journal
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

Tricyclic antidepressant overdoses cause significant harm and death. Prescribing safer medications is crucial for suicide prevention strategies.

Related Experiment Videos

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessing Meaningful Improvement: Focus on the Tinnitus Functional Index.

Ear and hearing·2024
Same author

The effect of bariatric surgery type on cardiac reverse remodelling.

International journal of obesity (2005)·2024
Same author

Changes in epicardial and visceral adipose tissue depots following bariatric surgery and their effect on cardiac geometry.

Frontiers in endocrinology·2023
Same author

Audiologic characteristics in a sample of recently-separated military Veterans: The Noise Outcomes in Servicemembers Epidemiology Study (NOISE Study).

Hearing research·2016
Same author

Reply to: Psychometric properties of the Tinnitus Functional Index (TFI): Assessment in a UK research volunteer population.

Hearing research·2016
Same author

Intra-operative frozen section analysis for suspected early-stage ovarian cancer: 11 years of Gateshead Cancer Centre experience.

BJOG : an international journal of obstetrics and gynaecology·2011
Same journal

Two cases of toxic epidermal necrolysis with severe ocular involvement treated with adjunctive tofacitinib.

Postgraduate medical journal·2026
Same journal

Diastolic dysfunction and diabetes: the DIADAD study-a retrospective cohort study from Liverpool.

Postgraduate medical journal·2026
Same journal

Care, cash, and proof: forensic accountability for war-related starvation.

Postgraduate medical journal·2026
Same journal

Response to traumatic injuries in polo players in England.

Postgraduate medical journal·2026
Same journal

Aids to venesection and parenteral drug administration in patients with difficult veins.

Postgraduate medical journal·2026
Same journal

Diagnostic reasoning in clinical neurology: a comprehensive primer.

Postgraduate medical journal·2026
See all related articles

Area of Science:

  • Pharmacology
  • Toxicology
  • Public Health

Background:

  • Antidepressant medications are widely prescribed for mood disorders.
  • Overdosage of certain antidepressants presents significant risks.

Purpose of the Study:

  • To review the problems associated with antidepressant overdosage.
  • To highlight the risks of tricyclic antidepressants (TCAs).

Main Methods:

  • Literature review of antidepressant overdosage cases.
  • Analysis of morbidity and mortality data associated with TCAs.

Main Results:

  • Tricyclic drugs are linked to high rates of illness and death in overdose cases.
  • Significant patient harm and mortality are associated with TCA toxicity.

Conclusions:

  • Reducing suicide requires careful consideration of medication safety in overdose.
  • Strategies for suicide reduction must prioritize antidepressants with lower overdose mortality.