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[Cushing's syndrome in pregnancy]
Vnitrni Lekarstvi
|January 1, 1995
Summary
Active Cushing's syndrome in pregnancy is rare, affecting 85 women historically. This case details a successful pregnancy outcome with adrenalectomy for a cortisol-producing adenoma.
Area of Science:
- Endocrinology
- Obstetrics
- Oncology
Background:
- Active Cushing's syndrome during pregnancy is exceptionally rare, with limited documented cases.
- Pregnancy complicates the management of hypercortisolism due to risks to both mother and fetus.
Observation:
- A patient presented with Cushing's syndrome during pregnancy.
- The patient delivered a healthy fetus via cesarean section at eight months gestation.
Findings:
- The patient's hypercortisolism and hyperaldosteronism were treated post-delivery with dextrolateral adrenalectomy.
- The removed adrenal gland contained a cortical adenoma composed of clear cells and cells resembling the zona glomerulosa.
Implications:
- This case highlights successful management of Cushing's syndrome in pregnancy.
- Understanding the prevalence, maternal-fetal impact, and optimal therapeutic strategies is crucial for managing this rare condition.